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WATCH: Tennis Channel Live discussed Anisimova's upset of Daria Kasatkina at the Western & Southern Open before her withdrawal.

Amanda Anisimova took to Instagram night to share the extent of a serious foot injury that contributed to her first-round exit from the US Open on Tuesday.

“I broke my toe in Cincinnati last week, and I’ve done everything I could to get ready for the Open,” the American wrote in a statement. “I’m proud of myself for giving myself a chance and playing the whole match. Even with getting injections in my foot that hurt more than the actual injury that I’m still recovering from lol.”

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A quarterfinalist at this year’s Wimbledon Championships, Anisimova was one of only two players to reach the second week of the first three major tournaments but withdrew from the Western & Southern Open ahead of her second-round clash with Shelby Rogers.

The 21-year-old was the No. 24 seed in Flushing Meadows, where she endured a 6-3, 6-3 loss to 2020 quarterfinalist Yulia Putintseva.

“I did all of this because I love this sport so much, even though it brings a lot of pain and disappointment. I hope I’ll be back stronger next year, and thank you to the crowd that is always the best here in New York. I love playing here.”

It is expected that Anisimova will likely miss the next several weeks of action to heal her broken toe.